The Biomedical Translational Research Information System (BTRIS) is a resource available to the NIH intramural community that brings together clinical research data from the Clinical Center and other NIH Institutes and Centers.  BTRIS provides clinical investigators with access to identifiable data for the subjects on their own active protocols, while providing all NIH investigators with access to de-identified data across all protocols.  BTRIS provides users with advanced search, filtering, and aggregation methods to create data sets to support ongoing studies and stimulate ideas for new research.  BTRIS Version 1.0 contains subject data from CRIS/MIS, NIAID (Crimson) and NIAAA.  Future versions of BTRIS will contain additional historical and clinical data back to 1976, images, and subject data from other IC Systems such as NCI.

BTRIS is two distinct but interrelated applications, BTRIS Data Access and BTRIS Preferences.  (Refer to the graphic below)

BTRIS Data Access is the data repository where principal investigators or their designee create reports on their active protocols with identified subject data.  The following reports will be available in BTRIS 1.0:  IRB Inclusion Enrollment Report, Patient Demographics, Patient Lists, Laboratory and Microbiology Results, Vital Signs, Medication orders and administration.  Additional reports will become available through the fall of 2009.   In September, 2009 access to de-identified data will begin for researchers within the NIH intramural program.

BTRIS Preferences is a Web based application that allows principal investigators or their designees to verify subject enrollment in their protocol(s).  This ensures that reports created in BTRIS Data Access include all subjects.  It also allows the principal investigator to designate an alternate investigator from the protocol to manage subject enrollment and create reports in BTRIS Data Access.

For questions or comment about BTRIS contact Dr. Jim Cimino, Chief, Laboratory for Informatics Development, NIH Clinical Center, National Institutes of Health, Bethesda, MD
   

This graphic shows the two applications within BTRIS; BTRIS Data Access and BTRIS Preferences. BTRIS Data Access allows researchers to access identified data on active protocols, or de-identified data with approval from the Office of Human Subjects Research. BTRIS Preferences allows researchers to attribute subjects to their protocols, designate alternate users, and set thresholds for e-mail notifications.

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